The Sanctum Sanctorum serves as the heroes' headquarters for a third of the game in Marvel: Ultimate Alliance.
Location History[]
The Sanctum Sanctorum is a three-story townhouse located at 177A Bleecker Street, "in the heart of New York City's Greenwich Village",
Marvel: Ultimate Alliance: Story[]
They move there from Stark Tower after learning of Loki's involvement in Doctor Doom's master plan (because he, disguised as Mandarin in Atlantis, managed to sidetrack the heroes' team from getting to Doom). From there, the player can access Murderworld (which first appears as a thinly-disguised Doom Castle, courtesy of a diversion spell by Baron Mordo) and Mephisto's Realm. If the player has Doctor Strange on their team, they can enter his room.